There certainly should be. Women typically have a narrower heel and taller arch than a man. So a boot that is billed as suitable for women should be built on a last (the mold used to form the boot) that reflects these characteristics, rather than simply taking a men聮s boot and down-sizing it.
La Sportiva Glacier Boot

And the Glacier ($250) is indeed built on a women聮s last and should be a good-fitting boot. Overall it聮s an excellent piece of footwear for heavy backpacking and light glacier mountaineering, with one-piece waterproof-leather uppers, a half-length steel shank for support, and tough toe rands for protection.
In the case of the Glacier, the women聮s model also comes in a pretty shade of blue, so that may be seen as a plus. Or not.
Another excellent boot to consider is the Charmoz GTX Lady ($260), which is similar in purpose to the Glacier, with a little more modern design. The Charmoz has a synthetic upper that聮s waterproof, as well as a Gore-Tex liner. It聮s lighter than the Glaciers, too聴nearly a pound lighter per pair. And it聮s built on a women聮s last for good fit.
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