Heck, yeah. The Sub Zero SL ($295) is designed for that kind of thing. It combines an ample amount of 650-fill down with a shell made from Mountain Hardwear聮s proprietary waterproof/breathable Conduit laminate. It聮s cut long for good coverage and has handy features such as an interior water-bottle pocket. It聮s perfectly good for Denali, and probably even for May climbs when it is really cold.
Mountain Hardwear Sub Zero SL Parka

I also like 聮s Greenland Baffled Down Jacket ($325). It聮s built with a little different design philosophy than the Sub Zero. It uses a higher grade of down (850 fill) and a water-resistant polyester shell, which in my view offers a little better breathability. So overall I think the Greenland may well be better suited for the cold, dry conditions you are apt to find on Denali. It聮s also a little bit lighter at 31 ounces, versus 37 ounces for the Sub Zero.
If you really feel like spending some money, it聮s very hard to beat 聮 Icefall Parka. It combines 850-fill down with an eVent shell, which makes it super-warm, waterproof, and very breathable. Weight is right between the two others I聮ve mentioned, 34 ounces. The price is sort of stratospheric, at $475, but it聮s a real investment in thermal well-being.
Hope you have a great trip!
The is now online so you can get prepped for gift-giving season聴even if everything you pick is for yourself!