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Don't rely on DNA splits for a negative split in your next race.
Don't rely on DNA splits for a negative split in your next race.

The Chromosome of Champions

Our genetic profile only tells one piece of the story, but that hasn't prevented scientists from making some bold assumptions about human performance.

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South Africa鈥檚 Sport and Recreation Minister, Fikile Mbalula, said something so upsetting, the statement sparked a , multiple news stories, and demands for an apology.

A journalist had asked Mbalula about the issue of racial equality on South Africa鈥檚 national teams, many of which are mostly white. His response, the , was this:

“You can't transform sports without targets,” said Mbalula, who has battled with the issue of racial quotas for some time. But at the same time, South Africa wouldn't be like Kenya and send athletes to the Olympics to 鈥渄rown in the pool.”

For Kenyans and members of other African countries, the statement was political, of endemic South African arrogance toward the rest of the continent. For researchers around the world, the backlash showed just how taboo it鈥檚 become to generalize about athletic performance according to race. Perhaps that鈥檚 one reason why genetic testing is heralded as the future of sports science: it takes the touchy issue of race out of athletics.

Take the case of the head of a physiology department at a big research university who David Epstein, author of , interviewed. 鈥淗e basically confessed to me that he was withholding data from publication because he found differences in his black and white subjects,鈥 Epstein says. The study looked into exercisers鈥 response to a dietary supplement. The researcher told Epstein he was afraid that by saying there were biological differences between black and white subjects, he鈥檇 be implying there might be intellectual differences, an old, wrong, and highly inflammatory stereotype. 鈥淏y falling prey to that notion, he might be perpetuating it,鈥 Epstein notes. The result of this scientist鈥檚 fear: athletes are left without the knowledge of a potentially useful or harmful supplement.

But imagine if that researcher could specify the gene responsible for the response he found. Then he could say the gene causes a certain issue and, by the way, it happens to be more prevalent in white or black people. A perfectly PC result.

That鈥檚 what the researchers who discovered the ACTN3 or 鈥渟print鈥 gene were able to do. The ACTN3 gene has been shown to contribute to 鈥渢he muscle鈥檚 ability to generate forceful, repetitive, muscle contractions,鈥 as writes. In other words, , author of Taboo: Why Black Athletes Dominate Sports and Why We鈥檙e Afraid to Talk About It, it helps make fast-twitch muscles fast.

found that all of them had a functional variant of that gene. The study took the approach outlined above. That is, researchers identified a gene related to sports performance, then remarked on how frequently a deficiency of this gene occurs in certain populations, like Europeans (18 percent) and the African Bantu population (less than 1 percent).

鈥淭his raises the possibility that ACTN3 genotype confers differential fitness in humans, under certain environmental conditions,鈥 the researchers wrote. A nice way of saying, essentially, that some black people may be more inherently gifted at sprinting than some white people.

Unfortunately, identifying specific genes, like ACTN3, and their purposes is tough to do. So at this point in time, relying on what little genetic knowledge we have to guide an athletic career can have disastrous consequences.

鈥淭here are some cases where a single gene causes a huge effect all by itself,鈥 Epstein explains. The brain disorder Huntington鈥檚 Disease, for example, is caused by a single defective gene. 鈥淏ut in most cases, genes work in huge networks and each one only has a tiny effect.鈥 Researchers don鈥檛 have a great idea of how that network works yet. So even if they find a gene related to athletic ability (and they have, in fact, ) it鈥檚 still too soon to do much with it.

鈥淭o make a decision based on that gene would be like having a puzzle鈥攜ou don鈥檛 even know how many pieces there are,鈥 Epstein says, 鈥渁nd making a decision based on only one of them without any of the others. You might need that piece to finish the puzzle, but you have no idea what that puzzle looks like without all the other pieces.鈥

The ACTN3 study led people to conclude that it鈥檚 impossible to run super fast without a functional variant of that gene. That鈥檚 a dodgy deduction, and because now that it鈥檚 easy to , athletes who find they lack it may turn away from sports at which they could excel.

So while genetic testing has much promise鈥攊n both mitigating Mbalula-like controversy and maximizing an individual鈥檚 athletic talent鈥攊t still has a long way to go before it鈥檚 truly helpful. Right now it鈥檚 silly, Epstein says, to test for an athletic trait like sprinting ability indirectly through genetics 鈥渨hen you can test it directly with a stopwatch.鈥

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